Welcome to the Hergenrother Lab!

With a guiding theme of using chemistry and small-molecules to identify, explore, and define novel targets for the treatment of disease, we aspire to make an impact in both chemistry and biology. We are both chemists and biologists, using the scientific techniques necessary to solve complex disease-driven questions.

​In the Hergenrother lab, we are fully committed to fostering a culture of diversity, inclusion, and equity in our lab and department. Our group welcomes all people with talent of all racial, cultural, and socioeconomic backgrounds, sexual orientations, and gender expressions to join us in our pursuit of scientific discovery. We pledge to be supportive of all individuals and maintain a collaborative and inclusive environment.

Latest News

• The Phase 1 clinical trial of PAC-1 in late-stage cancer patients shows responses in patients with neuroendocrine tumors
• Congratulations to graduate student Rebecca Ulrich for being awarded a F31 predoctoral fellowship from the NIH/NIAID!
• Read Young Innovator profile on Dr. Diana Ranoa, describing her pivotal role in developing the UIUC saliva test for COVID-19.
• A Phase 1B/2 clinical trial of PAC-1 for patients with metastatic uveal melanoma is now enrolling
• Congratulations to graduate student Matthew Boudreau for being awarded a prestigious fellowship from NCI!