Rebecca’s paper accepted in Biomaterials Science

Rebecca’s new paper, ‘The effect of glycosaminoglycan content on polyethylenimine-based gene delivery within three-dimensional collagen-GAG scaffolds,’ has been accepted in Biomaterials Science. In this collaboration with Prof. Dan Pack (Kentucky), Rebecca describes how the proteoglycan content of a collagen scaffold can be tuned to alter the efficiency of polyplex-based gene delivery vectors

Sara’s paper accepted in Advanced Materials [update: cover image!]

Congratulations to Sara Pedron and previous undergrad assistant Eftalda Becka for the acceptance of our new article, ‘Spatially-gradated hydrogel platform as a three-dimensional engineered tumor microenvironment,’ in Advanced Materials! The paper highlights Sara’s efforts using microfluidic patterning to create biomaterial avatars of glioblastoma multiforme, a common and deadly form of brain cancer.

Update (1/22/15): the work was just chosen for an inside back cover!

Craniofacial biomaterial project accepted by Biomaterials

Congratulations to Dan along with our collaborators at UCLA (Justine Lee, Tim Miller) for the acceptance of our new article, ‘Osteogenesis on nanoparticulate mineralized collagen scaffolds via autogenous activation of the canonical BMP receptor signaling pathway’ in Biomaterials. This paper is part of larger project between our groups investigating a new class of mineralized collagen biomaterials for regenerative repair of craniofacial defects. Great job!

Dan’s paper accepted in Biomaterials Science

Dan’s new paper, ‘Selective addition of mineral into collagen scaffolds to enhance hMSC osteogenesis and matrix remodeling,’ has been accepted in Biomaterials Science. The paper described recent advances developing mineralized collagen biomaterials to induce osteogenic differentiation of mesenchymal stem cells in the absence of osteogenic supplements.

Dr. Harley elected to AAAS

Dr. Harley is one of six University of Illinois at Urbana-Champaign faculty members (also Placid Ferreira, Joseph Lyding, Phil Newmark, Dan Roth, and William Sanders) that were elected as 2014 fellows of the American Association for the Advancement of Science. They are among the 401 new fellows chosen for their efforts to advance science applications that are deemed scientifically or socially distinguished. Dr. Harley (elected to the engineering section) and all the new fellows will be honored at the AAAS annual meeting in February 2015.

Lab awards at the BMES CMBE meeting

Dr. Harley and Rebecca will be traveling to the 2015 BMES CMBE meeting, ‘From Womb to Tomb: Mechanobiology of Generation, Regeneration, and Degeneration.’ Rebecca was chosen for a prestigious Student/Fellow Travel Award presentation and Dr. Harley will receive a CMBE Rising Star award.

Welcome Seema

The Harley Lab welcomes a new postdoc – Seema Ehsan. Seema received her PhD in Chemical Engineering from the University of California- Irvine working with Dr. Steve George. She will also be the theme fellow for the Regenerative Biology and Tissue Engineering theme at the IGB. Welcome!

Jackie wins Hanratty Travel Fellowship

Congrats to Jackie Pence for receiving a Hanratty travel fellowship from the ChBE department to support attending the 2014 TERMIS-NA meeting in Washington DC this December. Jackie will be presenting her work ‘Impact of hormone presentation on the recapitulation of endometrial Angiogenesis within a collagen-GAG scaffold.’ Great job!