Author: bharley@illinois.edu

Congratulations to Dr. Harley for acceptance of a new article, “Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment,” in Nature Cell Biology. This work is a continuation of efforts started by Dr. Harley’s as a post-doc in the laboratory of Dr. Les Silberstein.

Dr. Harley has been chosen to receive a 5-year, $400,000 National Science Foundation CAREER award in support of his project, ‘Building bone marrow.’ The goal of this effort is to develop a scalable bone marrow on a chip biomaterial system that acts a rheostat to control the growth and behavior of hematopoietic cells from the bone marrow.

Congratulations to Nate Gabrielson and Bhushan Mahadik for the acceptance of a their new article, ‘Cell-laden hydrogels in integrated microfluidic devices for long-term cell culture and tubulogenesis assays,’ in the journal Small. This work is part of a collaboration with Dr. Paul Kenis’s research groups.

Congratulations to Sara Pedron Haba for the acceptance of ‘The impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy,’ in the journal J. Biomed. Mater Res. Pt. A.

Congratulations to Dr. Harley for acceptance of a new article, ‘Focal adhesion kinase regulates the localization and retention of pro-B Cells in bone marrow microenvironments,’ in the Journal of Immunology. This work is part of a collaborative effort with Dr. Harley’s postdoctoral mentor, Dr. Les Silberstein.

Congratulations to Steven Caliari for acceptance of a new article, ‘Composite growth factor supplementation strategies to enhance tenocyte bioactivity in aligned collagen-GAG scaffolds,’ in Tissue Engineering Part A.

Dr. Harley is part of a team that has been chosen to receive a 3-year, $442,000 Dept. of Veteran’s Affairs award in support of their project, ‘Bone tissue engineering using mineralized collagen-GAG scaffolds.’ The goal of this effort is to investigate the use of mineralized collagen biomaterials to drive mesenchymal stem cell osteogenic differentiation for craniofacial bone regeneration. The PI for this project is Dr. Tim Miller (UCLA).

The Harley Lab welcomes a new graduate student – Bill Grier. Further congratulations for his selection as a CBI-TP trainee for 2013 – 2015!

Congratulations to Emily Gonnerman, Doug Kelkhoff, and Lisa McGregor for the acceptance of a new article, ‘The promotion of HL-1 cardiomyocyte beating using anisotropic collagen-GAG scaffolds,’ to appear in Biomaterials.

Congratulations to Sunny Choi for the acceptance of a new article, ‘The combined influence of substrate elasticity and ligand density on the viability and biophysical properties of hematopoietic stem and progenitor cells,’ to appear in Biomaterials.