The research in JNERL focuses on biosignal engineering and neural imaging to develop innovative solutions to advance neurorehabilitation and brain research.
The first goal of our research is to understand and quantitatively determine pathological changes in the nervous system that are associated with sensorimotor impairments in neurological disorders. This will address the important clinical needs of precision diagnosis and permit our second goal to develop more targeted therapeutical approaches that combat the symptoms of neurological disorders. Our interdisciplinary research integrates computational neuroscience approaches and human subject experiments, based on multi-modal brain imagining, non-invasive brain stimulation, electrophysiology signals, and robotic devices.
Targeted high-definition transcranial direct current stimulation (HD-tDCS) can improve motor pathway function and upper limb recovery in individuals with chronic stroke. The findings highlight the potential of individualized stimulation protocols to optimize rehabilitation outcomes by modulating CST and CRST excitability.
Hypothesis:
Following a stroke, the somatosensory system adapts to motor changes through an adaptive hemispheric shift of somatosensory processing toward the contralesional sensorimotor areas. This shift facilitates compensatory ipsilateral motor control by engaging contralesional S1 and M1, compensating for disrupted contralateral motor control due to the stroke lesion.
Framework of proposed multi-model brain imaging approach combining high-density EEG and diffusion weighted MRI to track the dynamic neural signal propagation in the brain.
