Before 2005

  1. Nair, S.K., and Burley, S.K. (2003) “X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors” Cell 112, 193-205.
  1. Campbell, E.A., Korzheva, N., Mustaev, A., Murakami, K., Nair, S., Goldfarb, A., and Darst, S.A. (2000) “Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase” Cell 104, 901-912.
  1. Nair, S.K., and Burley, S.K. (2000) “Recognizing DNA in the Library”, Nature (News and Views) 404, 715-718.
  1. Stams, T., Nair, S.K., Okuyama, T., Waheed, A., Sly, W.S., and Christianson, D.W. (1996) “Crystal Structure of the Secretory form of Membrane-associated Human Carbonic Anhydrase IV at 2.8-Å Resolution” Proc. Nat’l Acad. Sci. 93, 13589-13594.
  1. Elbaum, D., Nair, S.K., Patchan, M.W., Thompson, R.B., and Christianson, D.W. (1996) “Structure-Based Design of a Sulfonamide Probe for Fluorescence Anisotropy Detection of Zinc with a Carbonic Anhydrase-Based Biosensor” J. Am. Chem. Soc. 118, 8381-8387.
  1. Nair, S.K., Elbaum, D., and Christianson, D.W. (1996) “Unexpected Binding Mode of the Sulfonamide Fluorophore 5-Dimethylamino-1-napthalene Sulfonamide to Human Carbonic Anhydrase II” J. Biol. Chem. 271, 1003-1007.
  1. Nair, S.K., Krebs, J.F., Christianson, D.W., and Fierke, C.A. (1995) “Structural Basis of Inhibitor Affinity to Variants of Human Carbonic Anhydrase II” Biochemistry 34, 3981-3989.
  1. Ippolito, J.A., Nair, S.K., Alexander, R.S., Kiefer, L.L., Fierke, C.A., and Christianson, D.W. (1995) “Structure of His94àAsp carbonic anhydrase II in a new crystalline form reveals a partially occupied zinc binding site” Protein Eng. 8, 975-980.
  1. Nair, S.K., Ludwig, P.A., and Christianson, D.W. (1994) “Two-Site Binding of Phenol in the Active Site of Human Carbonic Anhydrase II: Structural Implications for Substrate Association” J. Am. Chem. Soc. 116, 3659-3660.
  1. Nair, S.K., and Christianson, D.W. (1993) “Structural Consequences of a Hydrophilic Amino Acid Substitution in the Hydrophobic Pocket of Human Carbonic Anhydrase II” Biochemistry 32, 4506-4514.
  1. Nair, S.K., and Christianson, D.W. (1993) “Crystallographic Studies of Azide Binding to Human Carbonic Anhydrase II” Eur. J. Biochem. 213, 507-515.
  1. Tweedy, N.B., Nair, S.K., Paterno, S.A., Fierke, C.A., and Christianson, D.W. (1993) “Structure and Energetics of a Non-Proline cis-Peptidyl Linkage in a Pro-202àAla Carbonic Anhydrase II variant” Biochemistry 32, 10944-10949.
  1. Nair, S.K., and Christianson, D.W. (1991) “Unexpected pH-Dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II” J. Am.Chem. Soc. 113, 9455-9458.
  1. Nair, S.K., and Christianson, D.W. (1991) “Structural Properties of Human Carbonic Anhydrase II at pH 9.5” Biochem. Biophys. Res. Commun. 181, 9455-9458.
  1. Nair, S.K., Calderone, T.L., Christianson, D.W., and Fierke, C.A. (1991) “Altering the Mouth of a Hydrophobic Pocket: Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121” J. Biol. Chem. 266, 17320-17325.
  1. Alexander, R.S., Nair, S.K., and Christianson, D.W. (1991) “Engineering the Hydrophobic Pocket of Carbonic Anhydrase II” Biochemistry 30, 11068-11072.

Recent Publications

2005-2012