- Agarwal, V., Borisova, S. A., Metcalf, W. W., van der Donk, W. A.*, and Nair, S. K.* (2011) “Structural and Mechanistic Insights into C-P Bond Hydrolysis by Phosphonoacetate Hydrolase.” Chem. Biol., 18, 1230-40 (*Corresponding author)
- Nair, S. K.(*), and Severinov, K. (*) (2011) “Microcin C7: Mechanism of Action and Bacterial Resistance.” Future Microbiology. 7, 281-9 (*Corresponding author)
- Agarwal, V. and Nair, S.K. (2011) Antibiotics and Emerging Pathogens. Spring Encyclopedia of Sustainability Science and Technology.
- Cobb, R., Bae, B., Zhao, H., and Nair, S. K. (2011) “A New Acetyltransferase Fold in the Structure and Mechanism of the Phosphonate Biosynthetic Enzyme FrbF.” J. Biol. Chem. 286, 36132-41
- Peck, S. C., Cooke, H. A. , Cicchillo, R.M., Malova, P. Hammerschmidt, F., Nair, S. K., and van der Donk, W. A. (2011) “Mechanism and Substrate Recognition of 2-Hydroxyethylphosphonate Dioxygenase.” Biochemistry, 50, 6598-605.
- McIntosh, J., Donia, M., Nair, S. K., and Schmidt, E. (2011) “Enzymatic Basis of Ribosomal Peptide Prenylation in Cyanobacteria.” J. Am. Chem. Soc. 133, 13698-705. [Highlighted in Chemical & Engineering News].
- Agarwal, V., Metlytskaya, A., Severinov, K., and Nair, S. K. (2011) “Structural Basis for Microcin C7 Inactivation by the MccE Acetyltransferase J. Biol. Chem. 286, 21295-303.
- Yoshida, S., Park, D. S., Bae, B., Mackie, R., Cann, I. K., Nair, S. K. (2011) “Structural and Functional Analyses of a Glycoside Hydrolase Family 5 Enzyme with an Unexpected β-Fucosidase Activity.” Biochemistry, 50, 3369-75.
- Li, Z., Rupasinghe, S. G., Schuler, M. A., Nair, S. K. (2011) “Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis.” Proteins 79, 1728-38.
- McIntosh, J. A., Robertson, C. R., Agarwal, V., Nair, S. K., Bulaj, G. W., Schmidt, E. W. (2010) “Circular logic: Nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst.” J. Am. Chem. Soc. 132, 15499-501.
- Lee, J.H. Bae, B., Kuemin, M., Circello, B.T., Metcalf, W.W., Nair, S.K.* and van der Donk, W.A.* (2010) “Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.” Proc. Nat’l Acad. Sci. USA. 107, 17557-62. (*Corresponding author)
- Nair, S. K.*, van der Donk, W.A.* (2010) “Structure and Mechanism of Enzymes Involved in the Biosynthesis and Breakdown of the Phosphonates Fosfomycin, Dehydrophos and Phosphinothricin.” Arch. Biochem. Biophys. 505, 13-21. (*Corresponding author)
- Su, X., Agarwal, V., Dodd, D., Bae, B., Mackie, R. I., Nair, S. K.*, Cann, I. K.* (2010) “Mutational insights into the roles of amino acid residues in ligand binding for two closely related family 16 carbohydrate binding modules.” J. Biol. Chem. 285, 34665-76. (*Corresponding author)
- Bae, B., Sullivan, R. P. Zhao, H., and Nair, S. K. (2010) Structure and Engineering of L-Arbinitol-4-Dehydrogenase from Neurospora crassa. J. Mol. Bio. 402, 230-40.
- Lin, L. J, Yoshinaga, A., Lin, Y., Guzman, C., Chen, Y. H., Mei, S., Lagunas, A. M., Koike, S., Iwai, S., Spies, M. A., Nair, S. K., Mackie, R. I., Ishino, Y., Cann, I. K. (2010) “Molecular Analyses of an Unusual Translesion DNA Polymerase from Methanosarcina acetivorans C2A.” J. Mol. Bio. 397, 13-30
- Lhee, S., Kolling, D. R., Nair, S. K., Dikanov, S. A., and Crofts, A. R., (2010) “Modifications of Protein Environment of the [2Fe-2S] Cluster of the bc1 Complex: Effects on the Biophysical Properties of the Rieske Iron-Sulfur Protein and on the Kinetics of the Complex.” J. Biol. Chem. 285, 9233-45.
- Zou, Y., and Nair, S.K. (2009) “Molecular Basis for the Recognition of Structurally Distinct Autoinducer Mimics by the Pseudomonas aeruginosa LasR Quorum Sensing Signaling Receptor.” Chemistry & Biology, 16, 961-970. [Highlighted with Editors Preview].
- Cicchillo, R. M., Zhang, H., Blodgett, J.A.V., Whitteck, J.T., Li, H., Nair, S.K.*, van der Donk, W.A.*, and Metcalf, W.W.* (2009) An Unusual Carbon-Carbon Bond Cleavage Reaction in the Biosynthesis of the Herbicide Phosphinothricin. Nature, 459, 871-74. (*Corresponding author) [Highlighted in Chemical & Engineering News, etc.].
- Bae, B., Chen, Y-H., Costa, A., Onesti, S., Brunzelle, J.S., Lin, Y., Cann, I.K.O. and Nair, S.K. (2009) Crystal structure of an archaeal MCM homolog provides insights into the architecture of the replicative helicase. Structure, 17, 211-22.
- Rubin-Pitel, S., Zhang, H., Vu, T., Brunzelle, J.S., Zhao, H.*, and Nair, S.K.* (2008) Unique Structural Elements Dictate the Specificity of the Type III Polyketide Synthase from Neurospora crassa. Chem. Biol., 15, 1079-1090. (*Corresponding author)
- Zou, Y., Brunzelle, J.S., and Nair, S.K. (2008) “Crystal structures of lipoglycopeptide antibiotic deacetylases: Implication for the biosynthesis of A40926 and Teicoplanin” Chem. Biol., 15, 533-45.
- Choi, Y.S., Zhang, H., Brunzelle, J.S., Nair, S.K.*, and Zhao, H.* (2008) “In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis.” Proc. Nat’l Acad. Sci. USA 105, 6858-63. (*Corresponding author)
- Bae, B., Ohene-Adjei, S., Kocherginskaya, Mackie, R. I., Spies, M.A., Cann, I. K. O.*, and Nair, S. K.* (2007) “Molecular Bases for the Specificity of Ligand Recognition by the Carbohydrate Binding Modules from Thermoanaerobacterium polysaccharolyticum manA.” J. Biol. Chem. 283, 12415-25. (*Corresponding author)
- Kolling, D., Brunzelle, J. S., Lee S., Crofts, A., and Nair, S K. (2007) “Atomic Resolution Structures of Rieske Iron-Sulfur Protein: Role of Hydrogen Bonds in Tuning Redox Potential of Iron-Sulfur Clusters”. Structure, 15, 29-38.
- Zou, Y., Li, C., Brunzelle, J.S., and Nair, S.K. (2006) “Crystallographic tracking of conformational changes during the catalytic reaction of an LPS biosynthetic enzyme”. Biochemistry 46, 4294-4304
- Kemp, M., Bae, B., Yu, J.P., Ghosh, M., Leffak, M., and Nair, S.K. (2006) “Structure and function of the DNA unwinding element binding protein: A regulator of DNA replication factor assembly” J. Biol. Chem. 282, 10441-10448.
- Dikanov, S.A., Kolling, D.R.J., Endeward, B., Samoilova, R.I., Prisner, T.F., Nair, S.K., and Crofts, A.R. (2006) “Identification of hydrogen bonds to the Rieske cluster through the weakly coupled nitrogens detected by ESEEM spectroscopy” J. Biol. Chem. 281, 27416-25.
- Lin, Y., Guzman, C.E., McKinney, M.C., Nair, S.K., Ha, T., Cann, I.K.O. (2006) “Methanosarcina acetivorans flap endonuclease 1 activity is inhibited by a cognate single-stranded DNA-binding protein”. J. Bacteriology, 188, 6153-6167.
- Lasker, M. V., and Nair, S. K. (2006) “Molecular Aspects of Signaling in the Innate Immune Response J. Immunology, 177, 11-16.
- Lasker, M.V., Kuruvilla, S., Kapoor, A., Gajjar, M., and Nair, S.K. (2006) “Metal Ion Mediated Reduction in Surface Entropy Improves Diffraction Quality of Crystals of the IRAK-4 Death Domain” J. Biomol. Techniques, 17, 114-121.
- Nair, S.K.*, and Burley, S.K. (2006) “Structural Aspects of Interactions Within the Myc/Max/Mad Network” The Myc/Max/Mad Transcription Factor Network. Eisenman, R.N., ed. Current Topics in Molecular Immunology 302, 123-144. (*Corresponding author)
- Li, B., Yu, J.P., Brunzelle, J.S., Moll, G.N., van der Donk, W.A.*, and Nair, S.K.* (2006) “Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis” Science, 311, 1464-67. [Highlighted in Chemical & Engineering News, etc.]. (*Corresponding author)
- Lasker, M.V., Gajjar, M,M., and Nair, S.K. (2005) “Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling.” J. Immunology 175, 4175-9.