Google Scholar h-index =  104    40,742 total citations

Last 4 years shown:

Gorfe, A. and Sligar, S.G. (2020) “Membrane Bound Ras as a Conformational Clock”  Biophysical Journal 118, 1-3.
Denisov, I.G., Schuler, M.A. and Sligar, S.G. (2019) “Nanodiscs as a New Tool to Examine Lipid-Protein Interactions.” In Kleinschmidt J. (eds) Lipid-Protein Interactions. Methods in Molecular Biology 2003, 645-671.  PMID: 31218635
Camp, T., Kritika, M., Sligar, S.G. and Zhang, K. (2020) “Molecular Orientation Determination in Nanodiscs at the Single Molecule Level” Analytical Chemistry  92, 2229-2236.
McLean, M.A., Stephen, A.G. and Sligar, S.G. (2019) “PIP2 Influences the Conformational Dynamics of Membrane Bound KRAS4b” Biochemistry 58, 3537-3545.
Ivanova, L., Denisov, I.G., Grinkova, Y.V., Sligar, S.G. and Faeste, C.K. (2019) “Biotransformation of the Mycotoxin Enniatin B1 by CYP P4503A4 and Potential for Drug-Drug Interactions” Metabolites 9, 158-175.
Ghazarian, H., Hu, W., Mao, A., Nguyen, T., Vaidehi, N., Sligar, S.G. and Shively, J.E. (2019) “NMR Analysis of Free and Lipid Nanodisc Anchored CEACAM1 Membrane Proximal Peptides with Ca(2+)/CaM”  Biochem. Biophys. Acta Biomembranes 1861, 787-797.
Camp, T., McLean, M., Kato, M., Cheruzel, L. and Sligar, S. G. (2019) “The Hydrodynamic Motion of Nanodiscs” Physics and Chemistry of Lipids, 220, 28-35.
Denisov, I.G., Grinkova, Y., Nandigrami, P., Shekhar, M., Tajkhorshid, E. and Sligar, S.G. (2019) “Allosteric Interactions in Human Cytochrome P450 CYP3A4:  The Role of Phenylalanine 213” Biochemistry 58, 1411-1422. PMC7003538
Wong, P., Li, L., Chea, J., Poku, E., Ebner, T. Bowkes, N., Wong, J. Y. C., Yazaki, P. J., Sligar, S. G., and Shively, J. E. (2019) “Antibody targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA positive tumors” Biochem. Biophys. Acta Biomembranes   in Press
Mustafa, G., Nandekar, P.P., Camp, T.J., Bruce, N.J., Gregory, M.C., Sligar, S.G. and Wade, R.C. (2019) “Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function” Biophysical Journal  116, 1-14. PMC6369400
Bu, R.L., Clark, J., DiChiara, T., Sligar, S.G. and Klein, W.L. (2018)  “SMPL Synaptic Membranes: Nanodisc-Mediated Synaptic Membrane Mimetics Expand the Toolkit for Drug Discovery and the Molecular Biology of the Synapses.”  Springer Nature Neuromethods 141, Synaptosomes (Murphy, K. M., ed.) pp. 227-250.
Duggal, R., Denisov, I.G. and Sligar, S.G. (2018)  “Cytochrome b5 Enhances Androgen Synthesis by Rapidly Reducing the CYP17A1 Oxy-complex in the Lyase Step” FEBS Letters 592, 2282-2288.    PMC6369587
Mak, P.J., Duggal, R., Denisov, I.G., Gregory, M.C. and Sligar, S.G. (2018)  “Human Cytochrome CYP17A1:  The Structural Basis for Compromised Lyase Activity with 17-Hydroxyprogesterone” J. American Chemical Society 140, 7324-7331.  PMC5999583
McLean, M. A., Gregory, M.C. and Sligar, S. G. (2018) “Nanodiscs: A Controlled Bilayer Surface for the study of Membrane Proteins” Annual Reviews Biophysics 47, 107-124.
Gregory, M.C., Mak, P.J., Khatri, Y., Kincaid, J.R. and Sligar, S.G. (2018) “Human CYP17A1: Control of Substrate Preference by Asparagine 202.”  Biochemistry 57, 764-771. PMC5801141.
Denisov, I.G., Baylon, J.L., Grinkova, Y.V., Tajkhorshid, E. and Sligar, S.G. (2018) “Drug-Drug Interactions Between Atorvastatin and Dronedarone Mediated by Monomeric CYP3A4” Biochemistry 57, 805-816.  PMC5800941.
Mak, P. J. and Denisov, I. G. (Sligar lab) (2018)  “Spectroscopic Studies of the Cytochrome P450 Reaction Mechanism.” BBA Proteins and Proteomics 1866, 178-204.
Wade J.H., Jones J.D., Lenov I.L., Riordan C.M., Sligar S.G. and Bailey R.C. (2017) “Microfluidic Platform for Efficient Nanodisc Assembly, Membrane Protein Incorporation and Purification”. Lab Chip 22, 2951-2959. PMID: 28767110, PMCID: PMC5589448.
Guo et al. (2017) Correction Cell Chemical Biology 24, 1314.
Guo Z., Sevrioukova, I.F., Denisov, I.G., Zhang, X., Chiu, T.L., Thomas, D.G., Hanse, E.A., Cuellar, R.A.D., Grinkova, Y.V., Langenfeld, V.W., Swedien, D.S., Stamschror, J.D., Alvarez, J., Luna, F., Galván, A., Bae, Y.K., Wulfkuhle, J.D., Gallagher, R.I., Petricoin, E.F. Rd, Norris, B., Flory, C.M., Schumacher, R.J., O’Sullivan, M.G., Cao, Q., Chu, H., Lipscomb, J.D., Atkins, W.M., Gupta, K., Kelekar, A., Blair, I.A., Capdevila, J.H., Falck, J.R., Sligar, S.G., Poulos, T.L., Georg, G.I., Ambrose, E., Potter, D.A. (2017) “Heme binding bi-guanidines target cytochrome P450 dependent cancer cell mitochondria” Cell Chemical Biology, 24, 1259-1275. PMC5650512.


DiChiara, T., DiNunno, N., Clark, J., Ru, R., Cline, E.N., Rollins, M.G., Gong, Y., Brody, D.L., Sligar, S.G., Velasco, P.T., Viola, K.L., and Klein, W. L.  (2017) “Alzheimer’s Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station”. Yale Journal of Biology and Medicine 90, 45-61.  PMC5369044.
Gregory, M.C., McLean, M.A. and Sligar, S.G. (2017) “Interaction of KRas4b with Anionic Membranes: A Special Role for PiP2” Biochemical and Biophysical Research Communications 487, 351-355.  PMC5509366.
Van Eps, N., Caro, L.N., Morizumi, T., Kusnetzow, A.K., Szczepek, M., Hoffman, K.P., Bayburt, T.H., Sligar, S.G., Ernst, O.P. and Hubbell, W. L. (2017) “Conformational Equilibria of Light Activated Rhodopsin in Nanodiscs”  Proc. Natl. Acad. Sci. USA  17, 2951-2959.  PMID: 287671108  PMCID PMC5402410.
Denisov, I.G. and Sligar, S.G. (2017) “Nanodiscs in Membrane Biochemistry and Biophysics” Chemical Reviews 117, 4669-4713. PMC5805400.
Ye, X., McLean, M.A. and Sligar, S. G. (2016) “PIP2 Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates its Auto-Inhibited Form”. Biochemistry  55, 5038-5048.
Her, C., Filoti, D.I., McLean, M.A., Sligar, S.G., Ross, J.B.A., Steel, H. and Laue, T.M. (2016) “The Charge Properties of Phospholipid Nanodiscs” Biophysical Journal 111, 989-998.
Ye, X., McLean, M.A. and Sligar, S.G., (2016) “Conformational Equilibrium of Talin is Regulated by Anionic Lipids.”  Biochemica et Biophysica Acta 1858, 1833-1840.  PMC5671925
Duggal, R., Liu, Y., Gregory, M., Denisov, I.D., Kincaid, J. and Sligar, S. G. (2016) “Evidence that Cytochrome b5 Acts as a Redox Donor in CYP17A1 Mediated Androgen Biosynthesis.”  Biochemical and Biophysical Research Communications 477, 202-208.
Denisov, I.G. and Sligar, S.G. (2016) “Nanodiscs for Structural and Functional Studies of Membrane Proteins.”  Nature Structural and Molecular Biology 23, 481-486.
Reichart, T. M., Baksh, M. M., Rhee, J.K., Fiedler, J. D., Sligar, S. G., Finn, M. G., Zwick, M. B. and Dawson P. E. (2016) “Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding.”  Angewandte Chemie Int. Edition 55, 2688-2692.
Denisov, I.G., Mak, P.J., Grinkova, Y.V., Bastien, D., Berube, G., Sligar, S.G. and Kincaid, J.R. (2016) “The Use of Isomeric Testosterone Dimers to Explore Allosteric Effects in Substrate Binding to Cytochrome P450 CYP3A4”, J. Inorganic Biochemistry 158, 77-85.
Mak, P.J., Gregory, M.C., Denisov, I.G., Sligar, S.G. and Kincaid, J.R. (2015) “Unveiling the Crucial Intermediates in Androgen Production” Proceedings National Academy of Sciences USA 112 (52), 15856-15861.
Skar-Gislinge, N., Kynde, S.A.R., Denisov, I. G., Ye, X., Lenov, I., Sligar, S.G., and Arleth, L. (2015) “Small Angle Scattering Determination of the Shape and Localization of Human Cytochrome P450 Embedded in a Phospholipid Nanodisc Environment.”  Acta Cryst. D71, 2412-2421.
Denisov, I. G., and Sligar, S. G. (2015)  “Metalloproteins:  The Long and Short Of It.”  Nature Chemistry News & Views, 7(9), 687-688.  PMID:  26291939
Wilcox, K. C., Marunde, M., Das, A., Velasco, P., Kuhns, B., Marty, M., Jiang, H., Lacor, P., Luan, C-H, Sligar, S. G., and Klein, W. L. (2015)  “Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen that Targets Binding Sites for Alzheimer’s-Associated Aß Oligomers.”  PLoS One 10(4), 1 (April 30) PMID: 25928376
Carney, C. E., Lenov, I. L., Baker, C. J., MacRenaris, K. W., Eckermann, A. L., Sligar, S. G., and Meade, T. J. (2015) “Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging.”  Bioconjugate Chemistry 26, 899-905.  PMID:  25830565
Denisov, I. G., Sligar, S. G. (2015) “Activation of Molecular Oxygen in Cytochromes P450.”  In: Cytochrome P450: Structure, Mechanism and Biochemistry, 4th ed. P. R. Ortiz de Montellano Ed., Springer International Publishing, Heidelbert-New York, p. 69-109.
Denisov, I. G., Grinkova, Y. V., Baylon, J. L., Tajkorshid, E., and Sligar S. G. (2015) “Mechanism of Drug-Drug Interactions Mediated by Human Cytochrome P450 CYP3A4 Monomer,” Biochemistry, 54, 2227-2239.  PMID:  25777547


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