2015

133. Xiong, M.; Lee, M.W.; Mansbach, R.A.; Song, Z.; Bao, Y; Jr. Peek, R. M.;  Yao, C; Chen, Lin-Feng; Ferguson, A.L.;  Wong, G.C.L.; Cheng, J. “Helical Antimicrobial Polypeptides with Radial Amphiphilicity”, PNAS, 2015, 112, 13155-13160. (1DP2OD007246, 1R21EB013379, R21AI117080, CHE-1153122; PMC4629321) [PDF] [SI] [Link]

132. Cai,K.; He, X.; Song, Z.; Yin, Q.; Zhang, Y.; Uckun, F.M.; Jiang, C.; Cheng, J. “Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency”, J. Am. Chem. Soc., 2015, 137, 3458-3461. (1DP2OD007246-01, 1R21CA152627, DMR 07-48834, NSF-DMR 1309525) [PDF] [SI] [Link]

131. Tang, L.; Yin, Q.; Xu, Y.; Zhou, Q.; Cai, K.; Yen, J.; Dobrucki, L.W.; Cheng, J. “Bioorthogonal Oxime Ligation Mediated in Vivo Cancer Targeting”, Chemical Science, 2015, 6, 2182-2186. (1DP2OD007246-01, DMR 07-48834; PMC4486360,NIHMS661301) [PDF] [Link]

130. Wu, X.; He, C.; Wu, Y.; Chen, X.; Cheng, J. “Nanogel-Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo-Protein Combination Therapy”, Advanced Functional Materials, 2015, 25, 6744-6755. [PDF] [SI] [Link]

129. Priftis, D.; Leon, L.; Song, Z.; Perry, S.L.; Margossian, K.O.; Tropnikova, A.; Cheng, J.; Tirrell M. “Self-Assembly of Alpha-Helical Polypeptides Driven by Complex Coacervation”, Angew. Chem. Int. Ed., 2015, 54, 11128-11132. (NSF-CHE1153122) [PDF] [SI] [Link]

128. Gauthier, M.; Yin, Q.; Cheng, J.; O’Brien W.D. “Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles”, J Ultrasound Med, 2015, 34, 1363-1372. (1DP2OD007246-01; PMC4536807,NIHMS712338) [PDF] [Link]

127. Lee, J.S.; Deng, X.; Han, P.; Cheng, J. “Dual Stimuli-Responsive Poly(beta-amino ester) Nanoparticles for On-Demand Burst Release”, Macromolecular Bioscience, 2015, 15, 1314-1322. (1DP2OD007246-01) [PDF] [SI] [Link]

126. Yin, Q.; Yin, L.; Wang, H.; Cheng, J. “Synthesis and biomedical applications of functional poly(alpha-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides”, Accounts of Chemical Research, 2015, 48, 1777-1787. (1DP2OD007246-01) [PDF] [Link]

125. Uckun, F.M.; Mitchell, L.G.; Qazi, S.; Myers, D.E.; Ma, H.; Zheng, N.; Song, Z.; Liu, Y.; Cheng, J. “Development of Polypeptide-Based Nanoparticles for Non-Viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL”, EBioMedicine, 2015, 2, 649-659. (1DP2OD007246-01, NSF-CHE 1308485; PMC4534679) [PDF] [Link]

124. Song, Z.; Kim, H.; Ba, X.; Baumgartner, R.; Lee, J.; Tang, H.; Leal, C.; Cheng, J. “Polypeptide Vesicles with Densely Packed Multilayer Membranes”, Soft Matter, 2015, 11, 4091-4098. (Dow Chemical Company, NSF-CHE 1308485) [PDF] [SI] [Link]

123. Uckun, F.M.; Qazi, S.; Cheng, J.; Myers, D.E. “Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-precursor Leukemia and Yield Superior Survival Outcomes in Mice EBioMedicine”, EBioMedicine, 2015, 2, 554-562. (1DP2OD007246-01; PMC4535154) [PDF] [Link]

122. Torabi, S.F.; Wu, P.; McGhee, C.E.; Chen, L.; Hwang, K.; Zheng, N.; Cheng, J.; Lu, Y. “In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing”, PNAS, 2015, 112, 5903-5908. (PMC4434688) [PDF] [Link]

121. Tang, L.; Tong, R.; Coyle, V.J.; Yin, Q.; Pondenis, H.; Borst, L.B.; Cheng, J.; Fan, T.M. “Targeting Tumor Vasculature with Aptamer Functionalized Doxorubicin-Polylactide Nanoconjugates for Enhanced Cancer Therapy”, ACS Nano, 2015, 9, 5072-5081. [PDF] [SI] [Link].

120. Uckun, F.M.; Qazi, S.; Cheng, J. “Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles”,Future Oncology, 2015, 11, 1149-1152. (1DP2OD007246-01) [PDF] [Link]

119. Baumgartner, R.; Song, Z.; Zhang, Y.; Cheng, J. “Functional Polyesters Derived from Alternating Copolymerization of Norbornene Anhydride and Epoxides”, Polymer Chemistry, 2015, 6, 3586-3590. (Dow Chemical Compay) [PDF] [SI] [Link]

118. Zhang, Y.; Yin, Q.; Yen, J.; Li, J.; Ying, H.; Wang, H.; Hua, Y.; Chaney, E.; Boppart, S.; Cheng, J. “Non-Invasive, Real-Time Reporting Drug Release In Vitro and In Vivo“, Chemical Communications, 2015, 51, 6948-6951. (1DP2OD007246-01;PMC4486253, NIHMS674723) [PDF] [SI] [Link]

117. Andrade, B.; Song, Z.; Li, J.; Zimmerman, S.; Cheng, J.; Moore, J.S.; Harris, K.; Katz, J. “New Frontiers for Encapsulation in the Chemical Industry”,  ACS Applied Materials & Interfaces, 2015, 7, 6359-6368. (Dow Chemical Company) [PDF] [Link]

116. Wang, H.C.; Zhang, Y.; Possanza, C.; Zimmerman, S.; Cheng, J.; Moore, J.; Harris, K.; Katz, J. ” Trigger Chemistries for Better Industrial Formulations”, ACS Applied Materials & Interfaces, 2015, 7, 6369-6382. (Dow Chemical Company) [PDF] [Link]

115. Wang, H.; Xu, M.; Xiong, M.H.; Cheng, J. ” Reduction-Responsive Dithiomaleimide-Based Nanomedicine with High Drug Loading and FRET-Indicated Drug Release “, Chemical Communications, 2015, 51, 4807-4810. (NSF-DMR 1309525, 1DP2OD007246-01; NIHMS666739) [PDF] [SI] [Link]

114. Zheng, N.; Song, Z.; Liu, Y.; Zhang, R.; Zhang, R.; Yao, C.; Uckun, F.M.; Yin, L.; Cheng, J. “Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery”, J. Controlled Release, 2015,205, 231-239. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01) [PDF] [Link]

113. Uckun, F.M.; Ma, H.; Cheng, J.; Myers, D.E.; Qazi, S. “CD22deltaE12 as a molecular target for RNAi therapy”, British Journal of Haematology, 2015, 169, 401-414. (1DP2OD007246-01) [PDF] [SI] [Link]

112. Cai, K.; Yen, J.; Yin, Q.; Liu, Y.; Song, Z.; Lezmi, S.; Zhang, Y.; Yang, X.; Helferich, W.G.; Cheng, J. “Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics”, Biomaterials Science, 2015, 3, 1061-1065. (DMR 07-48834, NSF-DMR 1309525, 1DP2OD007246-01, 1R21CA152627; NIHMS664361) [PDF] [SI] [Link]

111. Yin, L.; Chen, Y.; Zhang, Z.; Yin, Q.; Zheng, N.; Cheng, J. “Biodegradable Micelles Capable of Mannose-Mediated Targeted Drug Delivery to Cancer Cells”, Macromolecular Rapid Communications, 2015, 36, 483-489. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS683282) [PDF] [SI] [Link]

110. Ma, L.; Baumgartner, R.; Zhang, Y.; Song, Z.; Cai, K.; Cheng, J. “UV-Responsive Degradable Polymers Derived from 1-(4-Aminophenyl) ethane-1, 2-diol”, Journal of Polymer Science, Part A, 2015, 53, 1161-1168. (Dow Chemical Company) [PDF] [SI] [Link] [Cover]

109. Zhang, R.; Song, Z.; Yin, L.; Lu, H.; Gabrielson, N.P.; Cheng, J. “Ionic α-Helical Polypeptides towards Non-Viral Gene Delivery” WIREs Nanomedicine & Nanobiotechnolog, 2015, 7, 98-110. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS631933) [PDF] [Link]