| OBFS | Office of Business and Financial Services (UI) |
| OCR | Office of Corporate Relations |
| OHRP | Office of Human Research Protection |
| OHS | Occupational Health and Safety Programs |
| OIG | Office of Inspector General |
| OLAW | Office of Laboratory Animal Welfare |
| OMB | Office of Management and Budget |
| ONR | Office of Naval Research |
| OPD | Office of Proposal Development |
| OPRS | Office for the Protection of Research Subjects |
| ORAPD | Office of Research Advising and Project Development |
| ORI | Office of Research Integrity |
| ORNL | Oak Ridge National Laboratory (DOE) |
| OSHA | Occupational Safety and Health Administration |
| OSP | Office of Sponsored Programs |
| OTM | Office of Technology Managment |
| PA | Parent Announcement (NIH) |
| PAPPG | Proposal and Award Policies and Procedures |
| PE | Partial Execution |
| PHI/ePHI | Protected Health Information |
| PHS | U.S. Public Health Service |
| PI | Principal Investigator |
| PIRE | Partnerships for International Research and Education |
| PNNL | Pacific Northwest National Laboratory |
| POP/PEROP | Period of Performance |
| PRI | Prairie Research Institute |
| PTF | Proposal Transmittal Form |
| RAPD | Office of Research Advising and Project Development |
| RCR | Responsible Conduct of Research |
| RFA | Request for Application |
| RFP | Request for Proposal |
| RFQ | Request for Quotation |
| RPPR | Research Performance Progress Report |
| SBIR | Small Business Innovation Research |
| SBSRI | Social and Behavioral Sciences Research Initiative |
| SEOC | State Emergency Operations Center |
| SF424 | Standard Form 424 |
| SFI | Significant Financial Interest |
| SIAM | Society for Industrial and Applied Mathematics |
| SNL | Sandia National Laboratory (DOE) |
| SO | Signing Official |
| SOP | Standard Operating Procedure |
| SOW | Statement of Work |
| SPA | Sponsored Programs Administration |
| SPaRC | Sponsored Projects and Research Compliance Working Group |
| SRA | Sponsored Research Agreement |
| START | Systemwide Tools for Administration of Research and Training |
| STC | Science and Technology Center |
| STTR | Small Business Technology Transfer |
| TDC | Total Direct Costs |
| TTA | Technical Testing Agreement |
| UCAR | University Corporation for Atmospheric Research |
| UEO | Unit Executive Officer |
| UG | Uniform Guidance |
| URA | Universities Research Association, Inc. |
| USDA | United States Department of Agriculture |
| USGS | United States Geological Survey |