Studying the dynamic interactions of brain tumors with their native environment

We study the communication between brain tumors and the native tissue environment during tumor progression and after anticancer treatments. Our work focuses on the fabrication of tissue mimetic in vitro platforms to understand the critical role of the tumor microenvironment components in cancer progression and the key alterations induced by therapeutic intervention. These studies aim to better predict therapeutic outcomes and manipulate these interactions to develop innovative treatments.

We are committed to an inclusive and collaborative group culture that respects and values every member and aims to work together as a team. We collaborate with members of our department of Chemical and Biomolecular Engineering, the Carl R Woese Institute for Genomic Biology, Carle Illinois College of Medicine, and Cancer Center at Illinois to better understand the biological alterations in the brain tumor microenvironment to improve patient’s care and prognosis.