Publications

2022

Wang J, Xue X, Zeng H, Li J, Chen L-Q (2022).  Sucrose rather than GA transported by AtSWEET13 and AtSWEET14 supports pollen fitness at late anther development stages. New Phytologist, Accepted Author Manuscript. https://doi.org/10.1111/nph.18368

Mou Q, Xue X, Ma Y, Banik M, Garcia V, Guo W, Wang J, Song T, Chen L-Q & Lu Y (2022). Efficient delivery of a DNA aptamer-based biosensor into plant cells for glucose sensing through thiol-mediated uptake. Science Advances, 8(26):eabo0902.  (corresponding author)

Xue X, Wang J, Shukla D, Cheung SL, Chen L-Q (2022). When SWEETs Turn Tweens: Updates and Perspectives. Annual Review of Plant Biology 73. 

Wang J, Kambhampati S, Allen DK, Chen L-Q (2022). Comparative metabolic analysis reveals a metabolic switch in mature, hydrated, and germinated pollen in Arabidopsis thaliana. Frontiers in Plant Science  13:836665. https://www.frontiersin.org/article/10.3389/fpls.2022.836665

Chen L-Q (2022). Low sugar, under pressure? Nature Plants 8 (2):102-103. 

Chen Q, Hu T, Li X, Song CP, Zhu JK, Chen L-Q, Zhao Y (2022).  Phosphorylation of SWEET sucrose transporters regulates plant root: shoot ratio under drought. Nature Plants 8 (1):68-77. 

2021

Li Y, Li Q, Beuchat, G, Zeng H, Zhang C & Chen L-Q (2021). Combined analyses of translatome and transcriptome in Arabidopsis reveal new players responding to magnesium deficiency. Journal of Integrative Plant Biology 63(12):2075-92.  doi: 10.1111/jipb.13169

Zhang C, Li Y, Wang J, Xue, X, Beuchat G & Chen L-Q (2021). Two evolutionarily duplicated domains individually and post-transcriptionally control SWEETexpression for phloem transport. New Phytologist 232 (4):1793-1807

Wang J, Yu YC, Li Y and Chen L-Q (2022). Hexose transporter SWEET5 confers galactose sensitivity to Arabidopsis pollen germination via a galactokinase. Plant Physiology 189 (1):388-401

Wang J, Li Y, Wai CM, Beuchat G, Chen LQ (2021).  Identification and analysis of stem-specific promoters from sugarcane and energy cane for oil accumulation in their stems.  GCB Bioenergy.  13 (9): 1515-27

Xue X, Yu Y-C, Wu Y, Xue H, Chen L-Q (2021) Locally restricted glucose availability in the embryonic hypocotyl determines seed germination under ABA treatment.  New Phytologist 231 (5):1832-44

Li Y, Liu H, Yao X, Wang J, Feng S, Sun L, Ma S, Xu K, Chen L-Q, Sui X (2021). Hexose transporter CsSWEET7a in cucumber mediates phloem unloading in companion cells for fruit development. Plant Physiology  186 (1):640-54

Kim J-Y, Symeonidi E, Pang TY, Denyer T, Weidauer D, Bezrutczyk M, Miras M, Zöllner N, Hartwig T, Wudick MM, Lercher M, Chen L-Q, Timmermans MCP and Frommer WB (2021). Distinct identities of leaf phloem cells revealed by single cell transcriptomics. The Plant Cell. 33 (3), 511-30

2020

Beuchat G, Xue X, Chen L-Q (2020). Review: The next steps in crop improvement: adoption of emerging strategies to identify bottlenecks in sugar flux. Plant Scicence. 301, 110675.

Wang S, Liu S, Wang J, Yokosho K, Zhou B, Yu YC, Liu Z, Frommer WB, Ma JF, Chen L-Q†, Guan Y†, Shou H† and Tian Z† (2020). Simultaneous changes in seed size, oil content, and protein content driven by selection of SWEET homologues during soybean domestication. National Science Review 7 (11), 1776–86 (†corresponding author)

2019

Cheng, KJ, Selvam B, Chen L-Q, Shukla D (2019). Distinct substrate transport mechanism identified in homologous sugar transporters. The Journal of Physical Chemistry B 123 (40), 8411-18

Selvam B, YU YC, Chen L-Q and Shukla D (2019). Molecular basis of glucose transport mechanism in plants. ACS Central Science  5 (6), 1085-96

Wang H1†, Yan S1, Xin H, Huang W, Zhang H, Teng S, Yu YC, Lu X, Li P, Li S, Zhang C, Chen L-Q† and Lang Z† (2019). A subsidiary cell-localized glucose transporter is tightly associated with stomatal conductance and photosynthesis. The Plant Cell 31: 1328–43 ( 1equal contribution; †corresponding author)

Wang J, Li Y, Zhu F, Ming R and Chen L-Q (2019). Genome-wide analysis of nitrate transporter (NRT/NPF) family in sugarcane Saccharum spontaneum L. Tropical Plant Biology  12(3), 133-149

2018

Zeng H, Xia C, Zhang C and Chen L-Q (2018). A simplified hydroponic culture of ArabidopsisBio-protocolBio101: e3121 DOI: 21769/BioProtoc.3121.

Zhang J, Zhang X, Tang H, Zhang Q, Hua X, Ma X, Zhu F, Jones T, Zhu X, Bowers J, et al. (2018). Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L. Nature Genetics. 50: 1565-73

Zhang D, Kan X, Huss S. E, Jiang L, Chen L-Q, Hu Y (2018). Using phylogenetic analysis to investigate eukaryotic gene origin. Journal of Visualized Experiments (138), e56684, doi:10.3791/56684.

2017

Jia B, Zhu XF, Pu ZJ, Duan YX, Hao LJ, Zhang J, Chen L-Q, Jeon CO, and Xuan YH (2017). Integrative view of the diversity and evolution of SWEET and semiSWEET sugar transporters. Frontiers in Plant Science 8.

Cox KL, Meng F, Wilkins KE, Li F1, Wang P, Booher NJ, Carpenter SCD, Chen L-Q, Zheng H, Gao X, Zheng Y, Fei Z, Yu JZ, Isakeit T, Wheeler T, Frommer WB, He P, Bogdanove AJ, Shan L (2017). TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton.  Nature Communication 8: 15588

2016

Hu YB, Sosso D, Qu XQ, Chen L-Q, Ma L, Chermak D, Zhang DC & Frommer WB. (2016). Phylogenetic evidence for a fusion of archaeal and bacterial SemiSWEETs to form eukaryotic SWEETs and identification of SWEET hexose transporters in the amphibian chytrid pathogen Batrachochytrium dendrobatidis. The FASEB Journal. 30: 3644-54

2015 and before

Tao YY, Cheung LS, Li S, Eom JS, Chen L-Q, Xu Y, Perry K, Frommer WB & Feng L (2015). Structures of a eukaryotic SWEET transporter in a homotrimeric complex. Nature 527: 259-63

Eom JS, Chen L-Q, Sosso D, Julius BT, Lin IW, Qu XQ Braun DW and Frommer WB. (2015). SWEETs, transporters for intra- and intercellular sugar translocation. Current Opinion Plant Biology 25: 53-62

Chen L-Q, Lin IW, Qu XQ, Sosso D, Londoño A, McFarlane HE, Samuels AL, Frommer WB. (2015). A cascade of sequentially expressed sucrose transporters in the seed coat and endosperm provides nutrition for the Arabidopsis embryo. Plant Cell. 27: 607-19

Chen L-Q*, Cheung LS*, Feng L, Tanner W & Frommer WB. (2015). Transport of sugars. Annual Review of Biochemistry 84: 865-94 (*equal contribution)

Xu Y, Tao YY, Cheung LS, Fan C, Chen L-Q, Xu S, Perry K, Frommer WB & Feng L (2014) Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature 515: 448-52

Lin IW, Sosso D, Chen L-Q, Gase K, Kim SG, Kessler D, Klinkenberg PM, Gorder MK, Hou BH, Qu XQ, Carter CJ, Baldwin IT & Frommer WB (2014) Nectar secretion requires sucrose phosphate synthases and the sugar transporter SWEET9. Nature 508: 546-49

Chen L-Q (2014). SWEET sugar transporters for phloem transport and pathogen nutrition. New Phytologist  201: 1150-55

Xuan YH*, Hu YB*, Chen L-Q, Sosso D, Ducat DC, Hou BH & Frommer WB (2013). Functional role of oligomerization for bacterial and plant SWEET sugar transporter family. Proceedings of the National Academy of Sciences of the United States of America 110: 3685-94 (*equal contribution)

Jones AM, Grossmann G, Danielson JÅ, Sosso D, Chen L-Q, Ho CH & Frommer WB (2013) In vivo biochemistry: applications for small molecule biosensors in plant biology. Current Opinion in Plant Biology 16: 389-95

Liu L-L*, Ren H-M*, Chen L-Q, Wang Y & Wu W-H (2013). A protein kinase CIPK9 interacts with calcium sensor CBL3 and regulates K+ homeostasis under low-K+ stress in Arabidopsis. Plant Physiology 161: 266-77 (*equal contribution)

Frommer WB, Sosso D & Chen L-Q (2012). The SWEET glucoside transporter family. In: Encyclopedia of Biophysics, pp 2556-2558 (Roberts G., Ed.), Springer.

Chen L-Q*, Qu X-Q*, Hou B-H, Sosso D, Osorio S, Fernie AR & Frommer WB (2012). Sucrose efflux mediated by SWEET proteins as a key step for phloem transport. Science 335: 207-11. (*equal contribution)

Hou B-H, Takanaga H, Grossmann G, Chen L-Q, Qu X-Q, Jones AM, Lalonde S, Schweissgut O, Wiechert W & Frommer WB (2011). Optical sensors for monitoring dynamic changes of intracellular metabolite levels in mammalian cells. Nature Protocol 6: 1818-33

Chen L-Q, Hou B-H, Lalonde S, Takanaga H, Hartung M, Qu X-Q, Guo WJ, Kim JG, Underwood W, Chaudhuri B, Chermak D, Antony G, White FF, Somerville SC, Mudgett MB & Frommer WB (2010). Sugar transporters for intercellular exchange and nutrition of pathogens. Nature 468: 527-32

Xu J*, Li H-D*, Chen L-Q*, Wang Y*, Liu L-L*, He L & Wu W-H (2006). A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis. Cell 125: 1347–60. (*equal contribution)