Sources of Oxidative Stress

  1. Imlay, J. A. Diagnosing oxidative stress in bacteria: not as easy as you might think. Curr. Opin. Microbiol. 24C, 124–131 (2015).
  2. Kumar, S. R. & Imlay, J. A. How Escherichia coli tolerates profuse hydrogen peroxide formation by a catabolic pathway. J. Bacteriol. 195, 4569–4579 (2013).
  3. Liu, Y. & Imlay, J. A. Cell Death from Antibiotics Without the Involvement of Reactive Oxygen Species. Science (80-. ). 5691, 1210–1213 (2012).
  4. Korshunov, S. & Imlay, J. A. Two sources of endogenous hydrogen peroxide in Escherichia coli. Mol. Microbiol. 75, 1389–401 (2010).
  5. Hassett, D. J. & Imlay, J. A. Bactericidal antibiotics and oxidative stress: A radical proposal. ACS Chem. Biol. 2, 708–710 (2007).
  6. Korshunov, S. & Imlay, J. A. Detection and quantification of superoxide formed within the periplasm of Escherichia coli. J. Bacteriol. 188, 6326–34 (2006).
  7. Seaver, L. C. & Imlay, J. A. Are respiratory enzymes the primary sources of intracellular hydrogen peroxide? J. Biol. Chem. 279, 48742–50 (2004).
  8. Messner, K. R. & Imlay, J. A. Mechanism of superoxide and hydrogen peroxide formation by fumarate reductase, succinate dehydrogenase, and aspartate oxidase. J. Biol. Chem. 277, 42563–42571 (2002).
  9. Messner, K. R. & Imlay, J. A. In vitro quantitation of biological superoxide and hydrogen peroxide generation. Methods Enzymol. 349, 354–361 (2002).
  10. Woodmansee, A. N. & Imlay, J. a. Quantitation of intracellular free iron by electron paramagnetic resonance spectroscopy. Methods Enzymol. 349, 3–9 (2002).
  11. Seaver, L. C. & Imlay, J. A. Hydrogen Peroxide Fluxes and Compartmentalization inside Growing Escherichia coli. J. Bacteriol. 183, 7182–7189 (2001).
  12. Messner, K. R. & Imlay, J. A. The identification of primary sites of superoxide and hydrogen peroxide formation in the aerobic respiratory chain and sulfite reductase complex of Escherichia coli. J. Biol. Chem. 274, 10119–10128 (1999).
  13. Imlay, J. A. A metabolic enzyme that rapidly produces superoxide, fumarate reductase of Escherichia coli. Journal of Biological Chemistry 270, 19767–19777 (1995).
  14. Imlay, J. A. & Fridovich, I. Superoxide production by respiring membranes of Escherichia coli. Free Radic. Res. 12, 59–66 (1991).
  15. Imlay, J. A. & Fridovich, I. Assay of metabolic superoxide production in Escherichia coli. J. Biol. Chem. 266, 6957–65 (1991).
  16. Imlay, J. A. & Fridovich, I. Assay of metabolic superoxide production in Escherichia coli. J. Biol. Chem. 266, 6957–65 (1991).