A distinctive feature of CACHE is the integration of three contrasting, and complementary, initiatives. SPHERE examines the under-explored environment in United States residences with measurements and access approaches designed for scaling-up. The focus of GRAICES is basic services for households and communities around the world, especially in rural areas. SIMBAS develops future scenarios by leveraging the understanding of plausibility gained from SPHERE and GRAICES. Embedded in each of the three initiatives is a movement toward multidisciplinary integration of solutions and perspectives from physical and social sciences.