2021

27. Dean, AE, Reichardt, F, Anakk, S. Sex differences feed into nuclear receptor signaling along the digestive tract. Biochim Biophys Acta Mol Basis Dis. 2021 Jul 14;1867(11):166211. doi: 10.1016/j.bbadis.2021.166211. Online ahead of print. PMID: 34273530.

26. Mathur B, Shajahan A, Arif W, Chen Q, Hand NJ, Abramowitz LK, Schoonjans K, Rader DJ, Kalsotra A, Hanover JA, Azadi P, Anakk S. Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver. Sci Adv. 2021 Apr 21;7(17):eabf4865. doi: 10.1126/sciadv.abf4865. PMID: 33883138.

25. Nguyen JT, Riessen RR, Zhang T, Kieffer C, Anakk S. Deletion of intestinal SHP imapirs short-term response to cholic acid challenge in male mice. Endocrinology. 2021 Aug 1; 162(8):bqab063. doi: 10.1210/endocr/bqab063. PMID: 33769482.

24. Delgado ER, Erickson HL, Tao J, Monga SP, Duncan AW, Anakk S. Scaffolding protein IQGAP1 is dispensable, but its overexpression promotes hepatocellular carcinoma via YAP1 signaling. Mol Cell Biol. 2021 Mar 24;41(4):e00596-20. doi: 10.1128/MCB.00596-20. PMID: 33526450.

2020

23. Mathur B, Arif W, Patton ME, Faiyaz R, Liu J, Yeh J, Harpavat S, Schoonjans K, Kalsotra A, Wheatley AM, Anakk S. Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis. JHep Rep. 2020 Jul 2;2(5):100140. doi: 10.1016/j.jhepr.2020.100140. eCollection 2020 Oct. PMID: 32875282.

2018

22. Erickson HL, Anakk S. Identification of IQ motif-containing GTPase Activating Protein 1 as a regulator of long-term ketosis. JCI Insight. 2018 Nov 2;3(21). pii: 99866. doi: 10.1172/jci.insight.99866. [Epub ahead of print]. PMID: 30385723

21. Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A. Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration. Nat Struct Mol Biol. 2018 Oct;25(10):928-939. doi: 10.1038/s41594-018-0129-2. Epub 2018 Sep 24. PMID: 30250226

20. Kim KH, Choi JM, Li F, Arizpe A, Wooton-Kee CR, Anakk S, Jung SY, Finegold MJ, Moore DD. Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis. Endocrinology. 2018 Jun 1;159(6):2435-2446. doi: 10.1210/en.2018-00110. PMID: 29718219

2017

19. Akinrotimi O*, Riessen R*, VanDuyne P, Park JE, Wong LJ, Zavacki AM, Schoonjans K, Anakk S (*Co-first author). Shp deletion prevents hepatic steatosis and when combined Fxr loss protects against type 2 diabetes. Hepatology. 2017 Jun 6. doi: 10.1002/hep.29305. [Epub ahead of print]. PMID: 28586124

18. Kim KH, Choi S, Zhou Y, Kim EY, Lee JM, Saha PK, Anakk S, Moore DD. Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice. Hepatology. 2017 Aug;66(2):498-509. doi: 10.1002/hep.29199. Epub 2017 Jun 26. PMID: 28378930

17. Desai MS, Mathur B, Eblimit Z, Vasquez H, Taegtmeyer H, Karpen SJ, Penny DJ, Moore DD, Anakk S. Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart.
Hepatology. 2017 Jan; 65(1)189-201. doi: 10.1002/hep.28890. Epub 2016 Nov 29. PMID: 27774647

2015

16. Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A.
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.
Nat Commun. 2015 Nov 4;6:8768. doi: 10.1038/ncomms9768. PMID: 26531099

2014

15. Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS.
Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21.
PMID: 24365583

14. Kerr TA, Matsumoto Y, Matsumoto H, Xie Y, Hirschberger LL, Stipanuk MH, Anakk S, Moore DD, Watanabe M, Kennedy S, Davidson NO
Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism.
Hepatol Res. 2014 Oct;44(10):E218-28. doi: 10.1111/hepr.12230. Epub 2013 Oct 18.
PMID: 24033844

2013

13. Anakk S, Bhosale M, Schmidt VA, Johnson RL, Finegold MJ, Moore DD.
Bile acids activate YAP to promote liver carcinogenesis.
Cell Rep. 2013 Nov 27;5(4):1060-9. doi: 10.1016/j.celrep.2013.10.030. Epub 2013 Nov 21.
PMID: 24268772

12. Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M, Moore D, Timchenko NA
Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer.
Hepatology. 2013 Mar;57(3):1098-106. doi: 10.1002/hep.26146. Epub 2013 Feb 15.
PMID: 23172628

2011

11. Anakk S, Watanabe M, Ochsner SA, McKenna NJ, Finegold MJ, Moore DD.
Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.
J Clin Invest. 2011 Jan;121(1):86-95. doi: 10.1172/JCI42846. Epub 2010 Dec 1.
PMID: 21123943

10. Dwivedi SK, Singh N, Kumari R, Mishra JS, Tripathi S, Banerjee P, Shah P, Kukshal V, Tyagi AM, Gaikwad AN, Chaturvedi RK, Mishra DP, Trivedi AK, Sanyal S, Chattopadhyay N, Ramachandran R, Siddiqi MI, Bandyopadhyay A, Arora A, Lundåsen T, Anakk SP, Moore DD, Sanyal S
Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α.
Mol Endocrinol. 2011 Jun;25(6):922-32. doi: 10.1210/me.2010-0512. Epub 2011 Apr 14.
PMID: 21493670

9. Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, Yechoor V, Park J, Choi JS, Jang HC, Lee KU, Novak CM, Moore DD, Lee YK.
Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner.
J Lipid Res. 2011 Dec;52(12):2234-44. doi: 10.1194/jlr.M016048. Epub 2011 Sep 23.
PMID: 21949050

2007

8. Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW
Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
Drug Metab Dispos. 2007 Jan;35(1):36-42. Epub 2006 Oct 4.
PMID: 17020958

7. Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW.
Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes.
Arch Biochem Biophys. 2007 May 1;461(1):104-12. Epub 2007 Mar 15.
PMID: 17418803

2006

6. Kalsotra A, Zhao J, Anakk S, Dash PK, Strobel HW.
Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.
J Cereb Blood Flow Metab. 2007 May;27(5):963-74. Epub 2006 Sep 20.
PMID: 16985506

2005

5. Kalsotra A, Cui X, Anakk S, Hinojos CA, Doris PA, Strobel HW.
Renal localization, expression, and developmental regulation of P450 4F cytochromes in three substrains of spontaneously hypertensive rats.
Biochem Biophys Res Commun. 2005 Dec 9;338(1):423-31. Epub 2005 Aug 25.
PMID: 16182239

2004

4. Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW
CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
Pharmacogenomics J. 2004;4(2):91-101.
PMID: 14770174

2003

3. Anakk S, Ku CY, Vore M, Strobel HW.
Insights into gender bias: rat cytochrome P450 3A9.
J Pharmacol Exp Ther. 2003 May;305(2):703-9. Epub 2003 Feb 11.
PMID: 12606633

2. Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW
Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.
FASEB J. 2003 Sep;17(12):1736-8. Epub 2003 Jul 3.
PMID: 12958193

2002

1. Kalsotra A, Anakk S, Boehme CL, Strobel HW.
Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.
Drug Metab Dispos. 2002 Sep;30(9):1022-8.
PMID: 12167568