Hepatocyte-specific Deletion of a Splicing Regulatory Protein Causes NASH in Mice

Basic Science Poster

A20

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Hepatocyte-specific Deletion of a Splicing Regulatory Protein Causes NASH in Mice

Author/Presenter: Waqar Arif
Co-Author(s): Gandhar Datar, Qinyu Hao, Suthat Liangpunsakul, Sarath Junga, Jain Ma, RV Prasanth, Auinask Kalsotra


Ablation of SRSFI in the liver results in transscriptome wide changes. These changes eventually cause damage and development of non-alcoholic steatohepatitis.

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