Funding

We greatly appreciate the support from the School of Molecular Biology at UIUC, NIH/NIGMS, NIH/NIMH, and Research Corporation for Science Advancement.

Ongoing Research Support
R01GM132438                                Zhang (PI)                                            2019-2023
Sponsor: NIH/NIGMS
Precise regulation of native transcription factor at the single-cell level
The goal of this study is to develop an optogenetic approach to control the transcriptional activity of the native transcription factor.

Award #27937 Levy (PI), Ross (PI), Zhang (PI)                                           2021-2022
Sponsor: Research Corporation for Science Advancement
Engineering Enteric Neuron Activity to Enhance Antimicrobial Immunity in the Gut
The goal of this grant is to determine how ENS activity promotes antimicrobial immunity in the gut.

R01 MH124827                Tsai (PI) Zhang (MPI)                                           2020-2025
Sponsor: NIH/NIMH
Mechanism of Gp1 mGluR-dependent translation and plasticity
The goal of this study is to determine the role of mGluR dependent translation and neuronal plasticity.

R01 MH119149-01          Wang (PI) Zhang (CoI)                                           2019-2024
Sponsor: NIH/NIMH
Nonconventional role of ADCY in Gq-mediated neuronal signaling and neuroplasticity.
The goal of this study is to determine the role of adenylate cyclases (ADCY) in the development of neuroplasticity.

R01MH124992                  Wang (PI) Zhang (CoI)                                         2020-2024
Sponsor: NIH/NIMH
Mechanism underlying cognitive and synaptic flexibility
The goal of this study is to determine the role of adenylate cyclases 8-PI3K/Akt-GSK3β signaling in the regulation of synaptic depotentiation reversal/suppression of memory.

Completed Research Support
American Cancer Society PF-13-030-01-DDC         Zhang (PI)                      2013
Cell-fate determination by light-gated MAPK and AKT signaling pathways
The goal of this study is to compare the effects of light-activated MAPK and AKT pathways on cell proliferation and differentiation.

R56MH118908                         Wang (PI) Zhang (CoI)                                    2019-2020
Sponsor: NIH/NIMH
Mechanism underlying cognitive and synaptic flexibility
The goal of this study is to determine the role of adenylate cyclases 8-PI3K/Akt-GSK3β signaling in the regulation of synaptic depotentiation reversal/suppression of memory

R03NS120516                  Tsai (PI) Zhang (CoI)                                            2020-2021
Sponsor: NIH/NIMH
Study of PAK3 in epilepsy-associated defects in synaptic plasticity
The goal of this project is to determine how nuclear and cytoplasmic PAK3 contributes to epilepsy-associated defects in synaptic plasticity.