Publications

Selected Publications

Chowdhury MN, Jin H. The RGG motif proteins: Interactions, functions, and regulations. Wiley Interdiscip Rev RNA. 2022 Jun 3;:e1748. doi: 10.1002/wrna.1748.  PubMed PMID: 35661420; NIHMSID:NIHMS1809298.
Zeng F, Li X, Pires-Alves M, Chen X, Hawk CW, Jin H. Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Cell Rep. 2021 Oct 26;37(4):109877. doi: 10.1016/j.celrep.2021.109877. PubMed PMID: 34706231; PubMed Central PMCID: PMC9287898.
Zeng F, Jin H. Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination. Sci Rep. 2018 Feb 5;8(1):2349. doi: 10.1038/s41598-018-20107-8. PubMed PMID: 29403017; PubMed Central PMCID: PMC5799190.
Brandariz-Núñez A, Zeng F, Lam QN, Jin H. Sbp1 modulates the translation of Pab1 mRNA in a poly(A)- and RGG-dependent manner. RNA. 2018 Jan;24(1):43-55. doi: 10.1261/rna.062547.117. Epub 2017 Oct 6. PubMed PMID: 28986506; PubMed Central PMCID: PMC5733569.
Bao Y, Wu X, Chen J, Hu X, Zeng F, Cheng J, Jin H, Lin X, Chen LF. Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3993-E4001. doi: 10.1073/pnas.1700109114. Epub 2017 May 1. PubMed PMID: 28461486; PubMed Central PMCID: PMC5441817.
Zeng F, Chen Y, Remis J, Shekhar M, Phillips JC, Tajkhorshid E, Jin H. Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome. Nature. 2017 Jan 26;541(7638):554-557. doi: 10.1038/nature21053. Epub 2017 Jan 11. PubMed PMID: 28077875; PubMed Central PMCID: PMC5679781.
Zeng F, Jin H. Peptide release promoted by methylated RF2 and ArfA in nonstop translation is achieved by an induced-fit mechanism. RNA. 2016 Jan;22(1):49-60. doi: 10.1261/rna.053082.115. Epub 2015 Nov 9. PubMed PMID: 26554029; PubMed Central PMCID: PMC4691834.
Jin H, Kelley AC, Ramakrishnan V. Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15798-803. doi: 10.1073/pnas.1112185108. Epub 2011 Sep 8. PubMed PMID: 21903932; PubMed Central PMCID: PMC3179103.
Jin H, Kelley AC, Loakes D, Ramakrishnan V. Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8593-8. doi: 10.1073/pnas.1003995107. Epub 2010 Apr 26. PubMed PMID: 20421507; PubMed Central PMCID: PMC2889298.
Weixlbaumer A, Jin H, Neubauer C, Voorhees RM, Petry S, Kelley AC, Ramakrishnan V. Insights into translational termination from the structure of RF2 bound to the ribosome. Science. 2008 Nov 7;322(5903):953-6. doi: 10.1126/science.1164840. PubMed PMID: 18988853; PubMed Central PMCID: PMC2642913.
Jin H, Loria JP, Moore PB. Solution structure of an rRNA substrate bound to the pseudouridylation pocket of a box H/ACA snoRNA. Mol Cell. 2007 Apr 27;26(2):205-15. doi: 10.1016/j.molcel.2007.03.014. PubMed PMID: 17466623.