Brendan leads team awarded NSF MRI research award

Dr. Harley is the PI of a new research from the U.S. National Science Foundation entitled, ‘MRI: Acquisition of a 3D bioprinting system to generate composite biomaterials for regenerative medicine.’ This award will allow the Regenerative Biology and Tissue Engineering research theme at the IGB to acquire an Envison-TEC 3D Bioplotter. This 3D-printer will allow our theme new capabilities to fabricate large, geometrically complex, and cell-laden tissue biomaterials that mimic features of native tissues. Congrats to all involved, specifically all of the senior investigators and Co-PIs who helped make this application possible:  Rashid Bashir, Rohit Bhargava, Iwona Jasiuk, Kris Kilian, Hyun Joon Kong, Ceclia Leal, Larry Schook, Greg Underhill, Amy Wagoner Johnson, and Matt Wheeler!

Mai’s first paper accepted in Advanced Healthcare Materials

Congrats to Mai for the acceptance of her first paper, ‘The influence of hyaluronic acid and glioblastoma cell co-culture on the formation of endothelial cell networks in gelatin hydrogels,’ in Advanced Healthcare Materials. This study looks at the incorporating elements of the perivascular niche into gelatin hydrogels to explore the influence of glioblastoma-vascular interactions on GBM cell activity.

Brendan co-edits special journal issue: Gradient Biomaterials

Dr. Harley and Dr. Helen Lu (Columbia University) co-edited a Special Issue published in Acta Biomaterialia: Gradient in Biomaterials. This special issue highlighted some of the latest advances in developing biomaterials containing graded or non-uniform properties. The collection of scientific publications emphasized  existing challenges as well as opportunities in the fields of tissue engineering and regenerative engineering. Read it!

HarleyLab at #Biomaterials17

This week Brendan, Aidan, Mai, and Bill travel to the 2017 Society for Biomaterials annual meeting. Aidan Gilchrist has a podium presentation, ‘Tunable Biotransport Properties in Gelatin Hydrogels for Hematopoietic Stem Cell Culture,’ Wed 4:30p (#94, rm. 208CD). Mai Ngo has a podium presentation, ‘Impact of VEGF Presentation and Glioblastoma on Vascularization of GelMA,’ Thurs 11:00a (#133, rm 208CD). Bill Grier has a poster, ‘Combinatorial effects of cyclic tensile strain and local biomaterial cues on tendon-bone-junction engineering,’ Fri 2:15-3:45p (#867).

Brendan co-organizes NIDDK workshop on bone marrow remodeling

Brendan and Aidan travel to Washington this week to be part of a workshop Brendan helped organize with the NIDDK at the NIH. The goal of the Remodeling the Hematopoietic Bone Marrow Niche workshop is to bring together a multidisciplinary groups of researchers in a 1-day workshop format to learn more about the structure of the bone marrow, particularly the components of the niche that give rise to circulating blood cells and how the niche remodels to adequately respond to changes in environmental cues.

HarleyLab at #AACR17 meeting

This week Sara and Emily travel to the 2017 American Association for Cancer Research annual meeting. Emily Chen will be presenting her work on the effect of the matrix hyaluronic acid and hypoxia on invasive phenotype of glioblastoma, Sun 1p – 5p (Poster #931, section 43). Sara Pedron will be presenting work on the role of the matrix biophysical properties on GBM resistance to tyrosine kinase inhibitors, Wed 8a – 12p (Poster #5776, section 38).

Emily and Mai receive Conference Travel Awards

Emily Chen and Mai Ngo have each received Conference Travel Awards from the University of Illinois Graduate College. Emily will be attending the American Association for Cancer Research annual meeting to present a poster entitled, ‘Extracellular matrix stimuli regulate cancer stem cell population and migratory potential in glioblastoma.’ Mai will be attending the Society for Biomaterials annual meeting to present a podium talk entitled, ‘Impact of VEGF presentation and glioblastoma on vascularization of GelMA.’ Congratulations to both!

Alec and Raul awarded GRFP fellowships!

Excited to announce that first years Alec Tiffany AND Raul Sun Han Chang were both awarded a prestigious Graduate Research Fellowship by the NSF! Alec’s work focuses on biomolecule delivery methods to improve regenerative healing of craniofacial bone injuries. Raul is developing  methods to incorporate a compliant hydrogel zone into our collagen scaffold technology for osteotendinou (tendon-bone) repair. Congrats to both! Please see the ChBE news release about their award!